BASE bootcamp 2026

In this project, you will learn to:

• Design and optimize DNA-based diagnostic systems;

• Synthesis of DNA-zymes and G-quadruplex sensors;

• Isothermal amplification methods;

• Fluorescent and colorimetric detection;

• Sensor integration into microfluidic chips for point-of-care diagnostics.

In this project, you will learn to:

• Select expression vectors based on regulatory architecture;

• Design strategies to tune gene expression using regulatory elements;

• Perform controlled induction of gene expression;

• Extract total RNA from bacterial cultures and evaluate RNA quality;

• Quantify mRNA expression levels using RT-qPCR.

In this project, you will learn to:

• Obtaining target gene from a DNA template using PCR;

• DNA extraction and analysis;

• Cloning workflow: restriction (how to choose restriction enzymes and work with them), ligation, heat-shock transformation;

• Performing colony PCR;

• How T7 promoter works and protein expression.

• ​Определять границы устойчивости L. acidophilus к окислительному стрессу;

• Cинтез антимикробных соединений у пробиотика с помощью активных форм кислорода;

• ​Исследовать динамику секреции метаболитов в среду в зависимости от времени протекания стресс-реакции;

• ​Тестировать антибактериальную активность полученных фракций.

In this project you will learn to:

• Design experiments for gene overexpression in human cell cultures using CRISPRa;

• Transfection of genetic constructs into human cells;

• Evaluate the results of editing using qRT-PCR.

In this project, you will learn to:

• Synthesize antibody-conjugates;

• Perform SDS-PAGE for antibody analysis;

• Seed and maintain eukaryotic cell cultures;

• Work with atom emission spectroscopy.